Stockholm, October 6, 2025 — The Nobel Prize in Physiology or Medicine 2025 has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their pioneering discoveries concerning peripheral immune tolerance. Their research has significantly advanced our understanding of how the immune system distinguishes between harmful invaders and the body’s own tissues, preventing autoimmune diseases. Key Contributions: Sakaguchi subsequently linked these findings, showing that the Foxp3 gene regulates the development and function of Tregs. This connection established the foundation for the field of peripheral immune tolerance. The laureates’…
Read More2025 Nobel Prize in Medicine Awarded for Breakthroughs in Immune System Regulation
